Methodology to Calibrate the Dissection Properties of Aorta Layers from Two Sets of Experimental Measurements

Methodology to Calibrate the Dissection Properties of Aorta Layers from Two Sets of Experimental Measurements

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Aortic pride sundancer scooter dissection is a prevalent cardiovascular pathology that can have a fatal outcome.However, the mechanisms that trigger this disease and the mechanics of its progression are not fully understood.Computational models can help understand these issues, but they need a proper characterisation of the tissues.Therefore, we propose a methodology to obtain the dissection parameters of all layers in aortic tissue via the computational modelling of two different delamination tests: the peel and mixed tests.Both experimental tests have been performed in specimens of porcine aorta, where the intima-media and media-adventitia interfaces, as well as the medial layer, were dissected.

These two tests have been modelled using a cohesive zone formulation for the separating interface and a hyperelastic anisotropic material model joe moreira jiu jitsu via an implicit static analysis.The dissection properties of each interface have been calibrated by reproducing the force-displacement curves obtained in the experimental tests.The values of peak and mean force of the experiments were fitted with an error below 10%.With this methodology, we intend to contribute to the development of reliable numerical tools for simulating aortic dissection and aortic aneurysm rupture.